Shanghai Stem Cell Institute
|Focus||stem cell research|
|Key people||Professor Fanyi Zeng|
In 2007, the first Shanghai International Symposium on Stem Cell Research took place at Shanghai Jiatong University.
IPS cell breakthroughEdit
On July 24, 2009, the first publication of a successful breakthrough in Stem cell research was released, where Chinese researchers from the Shanghai Stem Cell Institute, led by Professor Fanyi Zeng, successfully reprogrammed adult stem cells to be able to differentiate into any body cell, as in the case with standard embryonic stem cells, the cells in question known as "induced pluripotent stem cells" (IPS cells). The IPS cells were obtained by genetically reprogramming the skin cells of mice to acts like embryonic stem cells, which then were able to differentiate into all forms of body tissue. The researchers have managed to use the IPS cells to create every type of cell in a mouse, creating entire mouse pups using the technique. This is the first time the technique has been used to make an entire mouse.
This breakthrough, published in the journals Nature and Cell Stem Cell and developed independently by two teams in China, may possibly depreciate the usage of stem cells obtained from human embryos. The oldest living mice created by the technique are nine months old and are reproducing, albeit showing signs of abnormalities. "This gives us hope for future therapeutic intervention using patients' own re-programmed cells in our far future," according to Professor Fanyi Zeng. A total of 27 mice were successfully born from the first generation of mice created from the IPS cells which were able to reproduce without any issues.
- Linzhao Cheng, Lei Xiao, Fanyi Zeng and Alex Zhang, 10 January 2008, Stem Cells Shine in Shanghai
- Chinese Scientists Reprogram Cells to Create Mice - WSJ
- Mice Research Shows Promise of Adult Stem Cells - TIME
- Mice Made From Mouse Skin Cells: Chinese Studies Confirm Potential of Skin Cells Reprogrammed to Act Like Embryonic Stem Cells - WebMD
- Mice pups bred from adult stem cells - Australian Broadcasting Corporation
- Mice made from induced stem cells - Nature News