SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 is a protein that in humans is encoded by the SMARCD1 gene .[ 5] [ 6] [ 7] [ 8]
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Two transcript variants encoding different isoforms have been found for this gene.[ 8]
^ a b c GRCh38: Ensembl release 89: ENSG00000066117 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023018 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Wang W, Xue Y, Zhou S, Kuo A, Cairns BR, Crabtree GR (Nov 1996). "Diversity and specialization of mammalian SWI/SNF complexes" . Genes Dev . 10 (17): 2117–30. doi :10.1101/gad.10.17.2117 PMID 8804307 . ^ Ring HZ, Vameghi-Meyers V, Wang W, Crabtree GR, Francke U (Sep 1998). "Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome" . Genomics . 51 (1): 140–3. doi :10.1006/geno.1998.5343 PMID 9693044 . ^ a b Hsiao PW, Fryer CJ, Trotter KW, Wang W, Archer TK (Aug 2003). "BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation" . Mol Cell Biol . 23 (17): 6210–20. doi :10.1128/MCB.23.17.6210-6220.2003 . PMC 180928 PMID 12917342 . ^ a b "Entrez Gene: SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1" .
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