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Sodium/myo-inositol cotransporter

  (Redirected from SLC5A3)

Sodium/myo-inositol cotransporter is a protein that in humans is encoded by the SLC5A3 gene.[5][6]

SLC5A3
Identifiers
AliasesSLC5A3, BCW2, SMIT, SMIT1, SMIT2, solute carrier family 5 member 3
External IDsOMIM: 600444 MGI: 1858226 HomoloGene: 31412 GeneCards: SLC5A3
Gene location (Human)
Chromosome 21 (human)
Chr.Chromosome 21 (human)[1]
Chromosome 21 (human)
Genomic location for SLC5A3
Genomic location for SLC5A3
Band21q22.11Start34,073,578 bp[1]
End34,106,260 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006933

NM_017391

RefSeq (protein)

n/a

NP_059087

Location (UCSC)Chr 21: 34.07 – 34.11 MbChr 16: 92.06 – 92.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Expression of the myo-inositol transport protein is regulated by osmotic stress.[7]

See alsoEdit

ReferencesEdit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198743 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000089774 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Berry GT, Mallee JJ, Kwon HM, Rim JS, Mulla WR, Muenke M, Spinner NB (Jul 1995). "The human osmoregulatory Na+/myo-inositol cotransporter gene (SLC5A3): molecular cloning and localization to chromosome 21". Genomics. 25 (2): 507–13. doi:10.1016/0888-7543(95)80052-N. PMID 7789985.
  6. ^ "Entrez Gene: SLC5A3 solute carrier family 5 (inositol transporters), member 3".
  7. ^ Lee SD, Choi SY, Lim SW, Lamitina ST, Ho SN, Go WY, Kwon HM (2011). "TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress: Organic osmolyte-dependent and -independent pathways". AJP: Renal Physiology. 300 (3): F707–F715. doi:10.1152/ajprenal.00227.2010. PMC 3064130. PMID 21209002.

Further readingEdit