SH2 domain-containing protein 3A is a protein that in humans is encoded by the SH2D3A gene.[3][4] The protein may be useful in Western Blots and ELISAs.[5]

SH2D3A
Identifiers
AliasesSH2D3A, NSP1, SH2 domain containing 3A
External IDsOMIM: 604721; HomoloGene: 48351; GeneCards: SH2D3A; OMA:SH2D3A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005490

n/a

RefSeq (protein)

NP_005481

n/a

Location (UCSC)Chr 19: 6.75 – 6.77 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Interactions

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SH2D3A has been shown to interact with the epidermal growth factor receptor.[3] The gene may play a role in JNK activation.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000125731Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b Lu Y, Brush J, Stewart TA (Apr 1999). "NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway". The Journal of Biological Chemistry. 274 (15): 10047–52. doi:10.1074/jbc.274.15.10047. PMID 10187783.
  4. ^ "Entrez Gene: SH2D3A SH2 domain containing 3A".
  5. ^ "Recombinant Human SH2D3A Protein". potassium-channel. Potassium Channel. 1 August 2017. Retrieved 18 September 2017.
  6. ^ "SH2D3A Gene". genecards.org. Gene Cards. Retrieved 18 September 2017.

Further reading

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