Phosphatidylcholine:ceramide cholinephosphotransferase 1 is an enzyme that in humans is encoded by the SGMS1 gene.[5][6][7]

SGMS1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSGMS1, MOB, MOB1, SMS1, TMEM23, hmob33, sphingomyelin synthase 1
External IDsOMIM: 611573; MGI: 2444110; HomoloGene: 27040; GeneCards: SGMS1; OMA:SGMS1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_147156

NM_001168525
NM_001168526
NM_144792
NM_001362423

RefSeq (protein)

NP_671512

NP_001161997
NP_001161998
NP_659041
NP_001349352

Location (UCSC)Chr 10: 50.31 – 50.63 MbChr 19: 32.12 – 32.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198964Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040451Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Vladychenskaya IP, Dergunova LV, Limborska SA (Feb 2002). "In vitro and in silico analysis of the predicted human MOB gene encoding a phylogenetically conserved transmembrane protein". Biomolecular Engineering. 18 (6): 263–8. doi:10.1016/S1389-0344(01)00110-1. PMID 11841947.
  6. ^ Yamaoka S, Miyaji M, Kitano T, Umehara H, Okazaki T (Apr 2004). "Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells". The Journal of Biological Chemistry. 279 (18): 18688–93. doi:10.1074/jbc.M401205200. PMID 14976195.
  7. ^ a b "Entrez Gene: TMEM23 transmembrane protein 23".

Further reading

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