Sphingosine-1-phosphate receptor 3 also known as S1PR3 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is also known as S1P3.[5]

S1PR3
Identifiers
AliasesS1PR3, EDG-3, EDG3, LPB3, S1P3, sphingosine-1-phosphate receptor 3
External IDsOMIM: 601965; MGI: 1339365; HomoloGene: 3829; GeneCards: S1PR3; OMA:S1PR3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005226

NM_010101

RefSeq (protein)

NP_005217

NP_034231

Location (UCSC)Chr 9: 88.99 – 89.01 MbChr 13: 51.56 – 51.58 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.[5]

Evolution

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See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000213694Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067586Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: S1PR3 sphingosine-1-phosphate receptor 3".
  6. ^ "GeneCards®: The Human Gene Database".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.