The Men's lightweight four event at the 2010 South American Games was held over March 22 at 11:20.
Medalists
edit| Gold | Silver | Bronze |
| Mario Cejas Nicolai Fernandez Carlo Lauro Pablo Manhic  Argentina
|
Miguel Angel Silva Rodrigo Santibanez Felipe Zbinden Fabian Zbinden  Chile
|
no medal |
Records
edit| World Best Time | ||||
|---|---|---|---|---|
| World best time |  Denmark
|
5:45.60 | Lucerne, Switzerland | 1999 |
Results
edit| Rank | Rowers | Country | Time |
|---|---|---|---|
|
Mario Cejas, Nicolai Fernandez, Carlo Lauro, Pablo Manhic | Argentina
|
6:21.25 |
|
Miguel Angel Silva, Rodrigo Santibanez, Felipe Zbinden, Fabian Zbinden | Chile
|
6:21.56 |
| 3 | Renato Azevedo, João Borges Junior, Renan Castro, Leandro Atoji |  Brazil
|
6:39.03 |