RhoGAP domain is an evolutionary conserved protein domain of GTPase activating proteins towards Rho/Rac/Cdc42-like small GTPases.

RhoGAP domain
Structure of Phospholipase A2.[1]
Identifiers
SymbolRhoGAP
PfamPF00620
InterProIPR000198
SMARTRhoGAP
PROSITEPDOC50238
SCOP21rgb / SCOPe / SUPFAM
OPM protein1xa6
CDDcd00159
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
PDB1xa6A:291-444 1f7cA:199-355 1am4B:260-408

1grnB:260-408 1ow3A:260-408 1rgp :260-402

1tx4A:260-408 2ngrB:260-408 1pbwB:129-281

Human proteins containing this domain

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ABR; ARHGAP1; ARHGAP10; ARHGAP11A; ARHGAP11B; ARHGAP12; ARHGAP15; ARHGAP17; ARHGAP18; ARHGAP19; ARHGAP20; ARHGAP21; ARHGAP22; ARHGAP23; ARHGAP24; ARHGAP25; ARHGAP26; ARHGAP27; ARHGAP28; ARHGAP29; ARHGAP30; ARHGAP4; ARHGAP5; ARHGAP6; ARHGAP8; ARHGAP9; BCR; BPGAP1; C1; C5orf5; CDGAP; CENTD1; CENTD2; CENTD3; CHN1; CHN2; DEPDC1; DEPDC1A; DEPDC1B; DLC1; FAM13A1; FKSG42; GMIP; GRLF1; HMHA1; INPP5B; KIAA1688; LOC553158; MYO9A; MYO9B; OCRL; OPHN1; PIK3R1; PIK3R2; PRR5; RACGAP1; RACGAP1P; RALBP1; RICH2; RICS; SH3BP1; SLIT1; SNX26; SRGAP1; SRGAP2; SRGAP3; STARD13; STARD8; SYDE1; SYDE2;

Notes

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  1. ^ Georgieva DN, Rypniewski W, Gabdoulkhakov A, Genov N, Betzel C (July 2004). "Asp49 phospholipase A(2)-elaidoylamide complex: a new mode of inhibition". Biochem. Biophys. Res. Commun. 319 (4): 1314–21. doi:10.1016/j.bbrc.2004.05.106. PMID 15194511.

References

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