RPP40

Ribonuclease P protein subunit p40 is an enzyme that in humans is encoded by the RPP40 gene.

RPP40
Identifiers
Aliases	RPP40, RNASEP1, bA428J1.3, ribonuclease P/MRP subunit p40
External IDs	OMIM: 606117; MGI: 1346084; HomoloGene: 4836; GeneCards: RPP40; OMA:RPP40 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p25.1 Start 4,994,717 bp End 5,004,063 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band 13|13 A3.3 Start 36,077,455 bp End 36,090,342 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad right adrenal cortex left adrenal gland endothelial cell mucosa of pharynx left adrenal cortex secondary oocyte gingival epithelium middle temporal gyrus Top expressed in morula embryo embryo lumbar spinal ganglion epiblast muscle of thigh blastocyst proximal tubule right kidney yolk sac More reference expression data BioGPS More reference expression data
Gene ontology Molecular function ribonuclease P activity hydrolase activity Cellular component nucleolus nucleus nucleolar ribonuclease P complex nucleoplasm Biological process RNA phosphodiester bond hydrolysis, endonucleolytic RNA phosphodiester bond hydrolysis tRNA processing tRNA 5'-leader removal Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10799 208366 Ensembl ENSG00000124787 ENSMUSG00000021418 UniProt O75818 Q8R1F9 RefSeq (mRNA) NM_001286132 NM_001286133 NM_006638 NM_145938 RefSeq (protein) NP_001273061 NP_001273062 NP_006629 NP_666050 Location (UCSC) Chr 6: 4.99 – 5 Mb Chr 13: 36.08 – 36.09 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Welting TJ, van Venrooij WJ, Pruijn GJ (2004). "Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex". Nucleic Acids Res. 32 (7): 2138–46. doi:10.1093/nar/gkh539. PMC 407822. PMID 15096576.