Silver proteinate

  (Redirected from Protargol)

Silver proteinate (brand name: Protargol) is used in electron microscopy with periodic acid and thiocarbohydrazide or thiosemicarbohydrazide as a positive stain for carbohydrates such as glycogen. It can also be used for light microscopy to stain nerve tissue. It is normally available as 8% silver in combination with albumin.[1]

Because of its bactericidal properties it was used to treat gonorrhea before the discovery of antibiotics. The inventor of the first silver protein formulation was Arthur Eichengrün, a German chemist working for Bayer. It was introduced for therapeutic use in 1897.[2][3]

See alsoEdit


  1. ^ Silver proteinate at Sigma-Aldrich
  2. ^ Vaupel, E. (2005), Arthur Eichengrün—Tribute to a Forgotten Chemist, Entrepreneur, and German Jew Angew. Chem. Int. Ed., 44: 3344–3355. doi: 10.1002/anie.200462959
  3. ^ State Medical Examining and Licensing Boards A Handbook of Useful Drugs: Protargol 1913 Press Of The American Medical Association (hosted on: