Prostanozol, also known as demethylstanozolol tetrahydropyran ether, is an androgen/anabolic steroid (AAS) and designer steroid which acts as a prodrug of the 17α-demethylated analogue of stanozolol (Winstrol). It was found in 2005 as an ingredient of products sold as "dietary supplements" for bodybuilding.[1]

Prostanozol
Clinical data
Other names17α-Demethylstanozolol 17β-tetrahydropyran ether; 17β-[(Tetrahydro-2H-pyran-2-yl)oxy]-5α-androst-2-eno[3,2-c]pyrazole; [3,2-c]Pyrazole-5α-etioallocholane-17β-tetrahydropyranol; 17β-[(Tetrahydro-2H-pyran-2-yl)oxy]-2'H-5α-androst-2-eno[3,2-c]pyrazole; Pyrazolo[4',3':2,3]-5α-androstan-17β-ol 17β-tetrahydropyran ether
Routes of
administration
By mouth
Drug classAndrogen; Anabolic steroid; Androgen ether
Identifiers
  • (1S,3aS,3bR,5aS,10aS,10bS,12aS)-10a,12a-dimethyl-1-((tetrahydro-2H-pyran-2-yl)oxy)-1,2,3,3a,3b,4,5,5a,6,7,10,10a,10b,11,12,12a-hexadecahydrocyclopenta[5,6]naphtho[1,2-f]indazole
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC25H38N2O2
Molar mass398.591 g·mol−1
3D model (JSmol)
  • C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2OC4CCCCO4)CC[C@@H]5[C@@]3(CC6=C(C5)NN=C6)C
  (verify)

It is one of hundreds of drugs banned from the Olympics by the IOC.[2] Russian marathon runner Lyubov Denisova was banned for two years from competition after testing positive for prostanozol and testosterone in 2007.[3]

References

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  1. ^ Eenoo PV, Delbeke FT (2006). "Metabolism and excretion of anabolic steroids in doping control—New steroids and new insights". Journal of Steroid Biochemistry and Molecular Biology. 101 (4–5): 161–178. doi:10.1016/j.jsbmb.2006.06.024. PMID 17000101. S2CID 33621513.
  2. ^ "192 Banned Performance Enhancing Substances and Methods". ProCon.org. March 17, 2010. Retrieved July 25, 2015.
  3. ^ "Russian marathon runner Denisova banned for 2 years for doping". USA Today. May 15, 2007. Retrieved July 25, 2015.