A preproenzyme is an enzyme with two additional characteristics: "pre" refers to a signal sequence (signal peptide) which directs the enzyme to a specific organelle or subcellular localization; "pro" indicates that the enzyme is present in an inactive form and requires modification (e.g. cleavage) for activation.[1]

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References

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  1. ^ Braun P, de Groot A, Bitter W, Tommassen J (1988). "Secretion of elastinolytic enzymes and their propeptides by Pseudomonas aeruginosa". J. Bacteriol. 180 (13): 3467–3469. doi:10.1128/JB.180.13.3467-3469.1998. PMC 107305. PMID 9642203.