Phellodendron amurense is a species of tree in the family Rutaceae, commonly called the Amur cork tree. It is a major source of huáng bò (Chinese: 黄柏 or 黄檗), one of the 50 fundamental herbs used in traditional Chinese medicine. The Ainu people used this plant, called shikerebe-ni, as a painkiller.
|Amur cork tree|
Morton Arboretum acc. 568-27*3
It is native to eastern Asia: northern China, northeast China, Korea, Ussuri,[clarification needed] Amur, and Japan, the Amur cork tree is considered invasive in many parts of North America. The State of Massachusetts lists it as a noxious weed.
Used orally to treat abdominal pain, diarrhoea, gastroenteritis and urinary tract infections. Phellodendron amurense may protect cartilage against osteoarthritis progression. It may prove to be a potentially important chemopreventive agent for lung cancer.
Phellodendron amurense is able to inhibit prostatic contractility suggesting that it may be useful in the treatment of urological disorders caused by prostatic urethral obstruction such as benign prostatic hyperplasia (BPH). Nexrutine (bark extract from Phellodendron amurense) may have potential to prevent prostate tumor development.
Compounds in the leaves (quercetin, quercetin-3-O-beta-D-glucoside, quercetin-3-O-beta-D-galactoside and kaempferol-3-O-beta-D-glucoside) demonstrated significant free radical scavenging activity comparable to vitamin E.
Amur cork tree fruit oil is a pressed oil extracted from the fruit of Phellodendron amurense. The bark of the tree is an important herbal medicine in China. The oil has insecticidal properties similar to pyrethrum. The oil contains a variety of biologically active substances, including flavonoids (diosmin), alkaloids (berberine, yatroriccin, palmatine), saponins and coumarins. Medicinal applications of the oil include treatment of pancreatitis, reduction of cholesterol and sugar in blood and the treatment of various skin diseases.
- Fruit oil contains myrcene (62.3–70.3%) and β-caryophyllene (6.8–10.5%)
- Leaf oil contains β-elemol (18.5%) and (Z)-β-ocimene (12.6%)
- Flower oil contains (Z)-β-ocimene (9.5%), β-elemol (9.4%), myrcene (7.8%) and nonacosane (7.7%)
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- Kim J.-H., Huh J.-E., Baek Y.-H., Lee J.-D., Choi D.-Y., Park D.-S."Effect of Phellodendron amurense in protecting human osteoarthritic cartilage and chondrocytes." Journal of Ethnopharmacology. 134 (2) (pp 234–242), 2011
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- Xu Y., Ventura S. "Extracts of bark from the traditional Chinese herb Phellodendron amurense inhibit contractility of the isolated rat prostate gland."Journal of Ethnopharmacology. 127 (1) (pp 196–199), 2010.
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- Garrison R., Chambliss W.G."Effect of a proprietary Magnolia and Phellodendron extract on weight management: A pilot, double-blind, placebo-controlled clinical trial". Alternative Therapies in Health and Medicine. 12 (1) (pp 50–54), 2006
- Leu C.-H., Li C.-Y., Yao X., Wu T.-S."Constituents from the leaves of Phellodendron amurense and their antioxidant activity." Chemical and Pharmaceutical Bulletin. 54 (9) (pp 1308–1311), 2006.
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- Lis A.; Boczek E.; Gora J. (2004). "Chemical composition of the essential oils from fruits, leaves and flowers of the Amur cork tree (Phellodendron amurense Rupr.)". Flavour and Fragrance Journal. 19 (6): 549–553. doi:10.1002/ffj.1349.
- Masao Hasegawa & Teruo Shirato (1953). "Two New Flavonoid Glycosides from the Leaves of Phellodendron amurense Ruprecht". J. Am. Chem. Soc. 75 (22): 5507–5511. doi:10.1021/ja01118a013.
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