Phase Genomics is an American biotechnology company based in Seattle, Washington. The company develops proximity ligation kits and Hi-C sequencing technology used to analyze chromosomes. Phase Genomics sells proximity ligation kits, scientific services, and computational analyses.
 | |
| Company type | Startup company |
|---|---|
| Industry | Biotechnology |
| Founded | 2015 |
| Founders | Ivan Liachko, Shawn Sullivan |
| Headquarters | Seattle, Washington, US |
Key people | Ivan Liachko (CEO, president), Shawn Sullivan (CTO) |
| Website | phasegenomics |
History
editThe company was founded by Ivan Liachko and Shawn Sullivan in 2015. It was originally housed in the CoMotion biotech incubator at University of Washington before relocating to a separate facility. It develops proximity ligation kits and Hi-C sequencing technology used to analyze chromosomes. The company sells proximity ligation kits, scientific services, and computational analyses.[1]
Research
editPhase Genomics developed a library preparation kit for the Hi-C sequencing method previously developed by researchers Job Dekker and Eric Lander. The kits are used to study the architecture of genomes.[2] In 2018, Phase Genomics received a $1.5 million SBIR grant from the National Institute of Allergy and Infectious Diseases (NIAID) to research antimicrobial resistance using Hi-C technology. In January 2020, it was awarded an additional $1.5 million from NIAID for phase 2 SBIR funding.[3] In 2019, Phase Genomics received $200,000 from the Bill & Melinda Gates Foundation to improve computational methods of extracting genomic data in microbiome samples.[3][4] Later in 2019, the company was awarded $325,000 from the U.S. Department of Energy to research algae biofuels using proximity litigation technology for metagenome assembly.[4] In 2020, Phase Genomics received 2 grants totaling $3.9 million from the National Human Genome Research Institute and the Eunice Kennedy Shriver National Institute of Child Health and Human Development. The 3-year grants fund research on chromosomal abnormalities causing cancer, infertility, and reproductive issues.[1]
In June 2021, the company released a platform for discovering new viruses in microbiome samples.[5][6]
References
edit- ^ a b Stiffler, Lisa (September 30, 2020). "Phase Genomics lands $3.9M in grants to improve testing for chromosomal abnormalities". GeekWire. Retrieved January 31, 2021.
- ^ LeMieux, Julianna (November 15, 2018). "Precision Medicine Looks beyond DNA Sequences". Genetic Engineering & Biotechnology News. 38 (20): 1, 22, 24–25. doi:10.1089/gen.38.20.02. ISSN 1935-472X. S2CID 239781336.
- ^ a b "Phase Genomics Wins $1.5M for Proximity Ligation-Based AMR Tracking". GenomeWeb. January 7, 2020. Retrieved January 31, 2021.
- ^ a b Kotrba, Ron (October 22, 2019). "Phase Genomics awarded DOE grant for algae biofuel research". Biodiesel Magazine. Retrieved January 31, 2021.
- ^ Gounot, Jean-Sebastien; Chia, Minghao; Bertrand, Denis; Saw, Woei-Yuh; Ravikrishnan, Aarthi; Low, Adrian; Ding, Yichen; Ng, Amanda Hui Qi; Tan, Linda Wei Lin; Teo, Yik-Ying; Seedorf, Henning; Nagarajan, Niranjan (October 13, 2022). "Genome-centric analysis of short and long read metagenomes reveals uncharacterized microbiome diversity in Southeast Asians". Nature Communications. 13 (1): 6044. Bibcode:2022NatCo..13.6044G. doi:10.1038/s41467-022-33782-z. ISSN 2041-1723. PMC 9561172. PMID 36229545.
- ^ "Phase Genomics Releases Platform for Discovering New Viruses in Microbiome Samples". www.businesswire.com. June 15, 2021. Retrieved December 7, 2022.