Pervomaisc may refer to several places in Moldova:
- Pervomaisc, Căuşeni, a commune in Căuşeni district
- Pervomaisc, Transnistria, a commune in Transnistria
- Pervomaisc, a village in Pompa Commune, Făleşti district
- Pervomaisc, a village in Lenin, Transnistria
- Pervomaisc, the Soviet-era name of Marienfeld village, Ialpujeni Commune, Cimişlia district