Payan or Payán is a surname. Notable people with the surname include:

  • Ana Rosa Payán, Mexican right-wing politician, Director of the National System for Integral Family Development
  • Benoît Payan (born 1978), French politician and mayor of Marseille
  • Claude-François de Payan (1766–1794), political figure of the French Revolution
  • Eliseo Payán (1825–1895), Colombian lawyer, politician, and military officer
  • Eugene Payan (1888–1971), Canadian ice hockey player
  • Ferdinand Payan (1870–1961), French bicyclist who competed in the first Tour de France
  • Ilka Tanya Payán (1943–1996), Dominican-born actress and attorney, later an HIV/AIDS activist in the United States
  • Joseph-François de Payan (1759–1852), political figure during the French Revolution, brother of Claude-François de Payan

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