Pleckstrin-2 is a protein that in humans is encoded by the PLEK2 gene.[5][6][7] The PLEK2 gene is located on chromosome 14 in Homo sapiens and is flanked by TMEM229B to its right and ATP6V1D to its left.[8]

PLEK2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPLEK2, pleckstrin 2
External IDsOMIM: 608007; MGI: 1351466; HomoloGene: 8447; GeneCards: PLEK2; OMA:PLEK2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016445

NM_013738

RefSeq (protein)

NP_057529

NP_038766

Location (UCSC)Chr 14: 67.39 – 67.41 MbChr 12: 78.94 – 78.95 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100558Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021118Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lemmon, Mark A.; Ferguson, Kathryn M.; Abrams, Charles S. (2002). "Pleckstrin homology domains and the cytoskeleton". FEBS Letters. 513 (1): 71–76. doi:10.1016/S0014-5793(01)03243-4. PMID 11911883.
  6. ^ Hamaguchi N, Ihara S, Ohdaira T, Nagano H, Iwamatsu A, Tachikawa H, Fukui Y (Aug 2007). "Pleckstrin-2 selectively interacts with phosphatidylinositol 3-kinase lipid products and regulates actin organization and cell spreading". Biochem Biophys Res Commun. 361 (2): 270–5. doi:10.1016/j.bbrc.2007.06.132. PMID 17658464.
  7. ^ "Entrez Gene: PLEK2 pleckstrin 2".
  8. ^ "AceView: PLEK2 gene". AceView. National Library of Medicine. Retrieved 24 April 2011.

Further reading

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