The PAQUID (or Paquid) cohort is a group of 3,777 individuals aged 65 years or older who were studied from 1988 until 2004.[1] Researchers selected participants for the group from at least 91 different areas of southwestern France to study the effects of different environmental, behavioral, and social vectors of age-related medical conditions and diseases. One of the major research goals was to determine some of the causes of dementia and Alzheimer's disease, such as the correlation between the levels of aluminum in drinking water and the occurrence of dementia.[2][3][1]
The studies were conducted by the Université Victor-Segalen, Bordeaux 2 (UB2) in Bordeaux, France.
The source of the term is "Personnes Agées QUID," which can be loosely translated from French and Latin as "What about the elderly?"[4]
See also edit
References edit
- ^ a b Rondeau, V.; Jacqmin-Gadda, H.; Commenges, D.; Helmer, C.; Dartigues, J.-F. (13 December 2008). "Aluminum and Silica in Drinking Water and the Risk of Alzheimer's Disease or Cognitive Decline: Findings From 15-Year Follow-up of the PAQUID Cohort". American Journal of Epidemiology. 169 (4): 489–496. doi:10.1093/aje/kwn348. PMC 2809081. PMID 19064650.
- ^ Nejjari, C; Tessier, JF; Baldi, I; Barberger-Gateau, P; Dartigues, JF; Salamon, R (October 1997). "[Epidemiologic aspects of respiratory aging: contribution of the PAQUID survey]". Revue d'épidémiologie et de santé publique. 45 (5): 417–28. PMID 9446147.
- ^ Helmer, C.; Damon, D.; Letenneur, L.; Fabrigoule, C.; Barberger-Gateau, P.; Lafont, S.; Fuhrer, R.; Antonucci, T.; Commenges, D.; Orgogozo, J. M.; Dartigues, J. F. (1 December 1999). "Marital status and risk of Alzheimer's disease: A French population-based cohort study". Neurology. 53 (9): 1953–1958. doi:10.1212/WNL.53.9.1953. PMID 10599764. S2CID 23832391.
- ^ Mazat, L.; Lafont, S.; Berr, C.; Debuire, B.; Tessier, J.-F.; Dartigues, J.-F.; Baulieu, E.-E. (26 June 2001). "Prospective measurements of dehydroepiandrosterone sulfate in a cohort of elderly subjects: Relationship to gender, subjective health, smoking habits, and 10-year mortality". Proceedings of the National Academy of Sciences. 98 (14): 8145–8150. doi:10.1073/pnas.121177998. PMC 35482. PMID 11427700.