Oswegatchie may refer to:
- In New York
- Oswegatchie, New York, a town in St. Lawrence County
- Oswegatchie River, a tributary of the Saint Lawrence River
- Oswegatchie people, a native people of northern New York
- Fort Oswegatchie, subsequent name of Fort de La Présentation
- Oswegatchie Corners, a location in the town of Diana, New York
- Elsewhere
- Oswegatchie Historic District, a location in the town of Waterford, Connecticut
This disambiguation page lists articles associated with the title Oswegatchie.
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