The boat was a whaler and weighed 328 tons. The boat was designed in Nantucket. The designer Aaron Mitchell of Nantucket, had Elijah and John B. Barstow of Barstow's Lower Shipyard in Hanover, build the Oeno on the North River, in the year 1821.
In November 1824, the crew on the boat began whaling in the South Pacific Ocean (According to William Cary, who was on the boat at the time). By March 17,1825, the crew had captured eight whales and used 150 barrels.
At approximately 2:AM on April 14, 1825, the boat crashed into a reef at Vatoa in Fiji. Only one person survived the crash, William Cary. The rest of the crew and the boat was massacred and killed by the Fijians in 1827. Shortly after returning to the United States, Cary claimed the ship was destroyed by the Natives at Vatoa.
- "Oeno Island". Pitcairn Islands Study Center. Pacific Union College. Retrieved 9 July 2020.
- The Whale Ship OENO. The North and South Rivers Watershed Association. Retrieved 2021-02-03.
- Dulles, Foster (1930). The Old China Trade. Cambridge, Massachusetts: Riverside Press. p. 100 – via University of Chicago.
- Philbrick, Nathaniel (2001). Sea of Glory: America's Voyage of Discovery, the U.S. Exploring Expedition, 1838-1842. Penguin Books.