OR4L1

Olfactory receptor 4L1 is a protein that in humans is encoded by the OR4L1 gene.

OR4L1
Identifiers
Aliases	OR4L1, OR14-28, OR4L2P, olfactory receptor family 4 subfamily L member 1, olfactory receptor family 4 subfamily L member 1 (gene/pseudogene)
External IDs	MGI: 3030558; HomoloGene: 71986; GeneCards: OR4L1; OMA:OR4L1 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) Band 14q11.2 Start 20,060,045 bp End 20,060,983 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 C1 Start 50,197,480 bp End 50,200,731 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle fundus n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 122742 258485 Ensembl ENSG00000176246 ENSMUSG00000096254 UniProt Q8NH43 K7N5X7 RefSeq (mRNA) NM_001004717 NM_146492 RefSeq (protein) NP_001004717 NP_666703 Location (UCSC) Chr 14: 20.06 – 20.06 Mb Chr 14: 50.2 – 50.2 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4L1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.