The Nizao River is one of the most important rivers in the Dominican Republic. Three hydroelectric power/electrical plants have been built along its path, the largest at Jiguey Dam. It is dried because of decade of aggregate extraction. Luis Carvajal, a top Dominican ecologist, estimated a cost of RD$350M per km to recover the river.
On 14 April 1655 Robert Venables landed with a contingent of the English New Model Army at the mouth of the Nizao River in preparation for a land attack on Santo Domingo. Vice-Admiral William Goodsonn was also landed with an auxiliary "sea regiment", composed of sailors. Their superior discipline enabled them to save the other soldiers from catastrophe during two Spanish ambushes. After two attempted assaults, the siege was abandoned.
- Jobin, William R.; Jobin, William (1999). Dams and disease: ecological design and health impacts of large dams, canals and irrigation systems. Taylor & Francis. pp. 157–158. ISBN 978-0-419-22360-3.
- "Archived copy". Archived from the original on 2014-04-26. Retrieved 2013-04-14.CS1 maint: archived copy as title (link)
- Plant, David. "The Western Design, 1655". bcw-project.org. british Civil Wars Project. Retrieved 29 May 2017.