Nicot is a French surname. Notable people with the surname include:

  • Adriano Nicot (born 1964), Cuban Neoexpressionist painter of French descendance
  • Emmanuelle Nicot (born 1985), French filmmaker and screenwriter
  • Jean Nicot (1530–1600), French diplomat and scholar
  • Jean-Louis Nicot (1911–2004), commander of the French Air transport fleet during the First Indochina War
  • Juan Mercado-Nicot (27 August 1862 - 25 January 1954), son of Jose Antonio Mercado and Ramona Nicot
  • Ramona Nicot (Abt. 1827 - 13 July 1909), daughter of Francisco Nicot and Maria Francisca Bernazar

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