Nichols is an English surname. It is an anglicised form of the Scottish surname relating to Clan MacNeacail, and may refer to:

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  • Kathleen Nichols, American computer scientist and computer networking expert
  • Kelly Nichols, former pornographic actress
  • Keith Nichols (1945–2021), English jazz multi-instrumentalist and arranger
  • Kenneth Nichols, District Engineer of the Manhattan Project
  • Kid Nichols (1869–1953), Major League Baseball (MLB) pitcher who played for the Boston Beaneaters, St. Louis Cardinals and Philadelphia Phillies
  • Kyra Nichols, American ballet dancer and teacher, former New York City Ballet principal dancer

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  • Vincent Gerard Nichols, English cardinal of the Roman Catholic Church, Archbishop of Westminster and President of the Catholic Bishops' Conference of England and Wales

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