A neuroma (/njʊəˈrmə/; plural: neuromata or neuromas) is a growth or tumor of nerve tissue.[1] Neuromas tend to be benign (i.e. not cancerous); many nerve tumors, including those that are commonly malignant, are nowadays referred to by other terms.

Solitary circumscribed neuroma
SpecialtyOncology Edit this on Wikidata

Neuromas can arise from different types of nervous tissue, including the nerve fibers and their myelin sheath, as in the case of genuine neoplasms (growths) like ganglioneuromas and neurinomas.

The term is also used to refer to any swelling of a nerve, even in the absence of abnormal cell growth. In particular, traumatic neuroma results from trauma to a nerve, often during a surgical procedure. Morton's neuroma affects the foot. Neuromas can be painful, or sometimes, as in the case of acoustic neuromas, can give rise to other symptoms.

Neoplasms edit

Other nerve swellings edit

Some of the benign varieties of neuroma, in the broadest sense of the term, are not neoplasms.

  • Traumatic neuroma follows different forms of nerve injury (often as a result of surgery). They occur at the end of injured nerve fibres as a form of ineffective, unregulated nerve regeneration; it occurs most commonly near a scar, either superficially (skin, subcutaneous fat) or deep (e.g., after a cholecystectomy). They are often very painful. Synonyms include scar neuroma, amputation neuroma, or pseudoneuroma.
  • Morton's neuroma (a mononeuropathy of the foot) is another example of the more general usage of the term neuroma. Some prefer the term "Morton's metatarsalgia", thus avoiding the term neuroma and its association with tumors.[6]

Etymology edit

The stem neuro- originates from the Greek word for nerve (νεῦρον), while the suffix -oma (-ωμα) denotes swelling.[7] The stem does not imply that neuromas necessarily arise from neurons; neuromas generally arise from non-neuronal nerve tissues. The word was originally used to refer to any nerve tumor, but its meaning has evolved.[7]

References edit

  1. ^ "Neuroma". Dorland's Illustrated Medical Dictionary (32nd ed.). Oxford University Press. 2011. p. 5287. ISBN 978-1-4557-0985-4. Retrieved 25 August 2013.
  2. ^ "Acoustic Neuroma". NHS Choices. Retrieved 30 August 2013.
  3. ^ "Acoustic neuroma". PubMed Health. A.D.A.M. Medical Encyclopedia. NLM. Retrieved 21 December 2014.
  4. ^ Gross, Kenneth (2006-09-25). "Ganglioneuroma". Retrieved 2007-05-09.
  5. ^ Zanardi F, Cooke RM, Maiorana A, Curti S, Farioli A, Bonfiglioli R, Violante FS, Mattioli S (2011). ""Is this case of a very rare disease work-related?" A review of reported cases of Pacinian neuroma". Scand J Work Environ Health. 37 (3): 253–8. doi:10.5271/sjweh.3132. hdl:11380/738485. PMID 21082159.
  6. ^ "Morton's metatarsalgia". GPnotebook.
  7. ^ a b "neuroma". Oxford English Dictionary (Online ed.). Oxford University Press. (Subscription or participating institution membership required.)