NSMB may refer to:
- NSMB (mathematics), a Navier-Stokes finite volume solver
- Nature Structural & Molecular Biology, an academic journal
- New Super Mario Bros. (series), a series of 2D platform games by Nintendo consisting of new revivals of classic Mario platformers
- New Super Mario Bros., the first game in the series, released in 2006 for the Nintendo DS
- nsmb(4), Server Message Block implementation on FreeBSD and other BSD systems including macOS
This disambiguation page lists articles associated with the title NSMB.
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