Moccasin Creek may refer to:
- Moccasin Creek (Uwharrie River tributary), a stream in Montgomery County, North Carolina
- Moccasin Creek (South Dakota), a creek in South Dakota
- Moccasin Creek (Wisconsin), a creek in Wisconsin
- Moccasin Creek State Park, a state park in Georgia
This disambiguation page lists articles about distinct geographical locations with the same name.
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