Mitragyna diversifolia

Mitragyna diversifolia[2] is a tree species in the family Rubiaceae and found in Asia.[3][4] The Catalogue of Life lists no subspecies.[3]

Mitragyna diversifolia
Illustrated as "Stephegyne diversifolia"
Scientific classification Edit this classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Asterids
Order: Gentianales
Family: Rubiaceae
Genus: Mitragyna
Species:
M. diversifolia
Binomial name
Mitragyna diversifolia
Synonyms

Stephegyne tubulosa Fern.-Vill.
Stephegyne parvifolia Vidal
Stephegyne diversifolia (Wall. ex G.Don) Hook.f.
Stephegyne diversifolia (Wall. ex G.Don) Brandis
Nauclea diversifolia Wall. ex G.Don
Nauclea adina Blanco
Mitragyna javanica Koord. & Valeton
Mamboga capitata Blanco

Description

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Mitragyna diversifolia is a deciduous under-story tree, that reaches up to 15 m in height. The branches are angled and cylindrical. The leaves are ovate-oblong to elliptic-ovate, averaging 146 × 93 mm in size, obtuse apex to shortly acuminate. The yellow corolla has white lobes. The fruit in the form of a capsule of 3–4 mm.[5]

Distribution

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It is distributed through the forests of China (Yunnan), Cambodia, Indonesia, Laos, Burma, the Philippines, Thailand and Vietnam.

Uses

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The genus mitragyna has been used traditionally to alleviate symptoms of fever, coughing, diarrhea, muscular pain and deworming,[6] although antioxidant and antimicrobial properties have also been found.[7] Typically these are consumed as a whole leaf or powder form, although gel-capsules, containing powder, are also used. Mitragyna diversifolia has been shown to possess pharmacological antidiarrheal properties, as well as analgesic properties.[8]

Phytochemicals

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Mitragyna diversifolia leaf contains the alkaloids 7-hydroxy-isopaynantheine, 3-dehydro-paynantheine, 3-isopaynantheine-N(4)- oxide, mitrafoline, mitradiversifoline, specionoxeine-N(4)-oxide, specionoxeine-N(4)-oxide.[9]


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References

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  1. ^ The Plant List: Mitragyna diversifolia (accessed 3/6/2013
  2. ^ Haviland GD (1897) Journal of the Linnean Society, Botany 33: 71.
  3. ^ a b Roskov Y.; Kunze T.; Orrell T.; Abucay L.; Paglinawan L.; Culham A.; Bailly N.; Kirk P.; Bourgoin T.; Baillargeon G.; Decock W.; De Wever A. (2014). Didžiulis V. (ed.). "Species 2000 & ITIS Catalogue of Life: 2014 Annual Checklist". Species 2000: Reading, UK. Retrieved 26 May 2014.
  4. ^ WCSP: World Checklist of Selected Plant Families
  5. ^ Mitragyna diversifolia in Flora of China
  6. ^ Gong, Fang; Gu, Hai-Peng; Xu, Qi-tai; Kang, Wen-yi (2012). "Genus Mitragyna: Ethnomedicinal uses and pharmacological studies" (PDF). Phytopharmacology. 3 (2): 263–272. Retrieved 17 June 2020.
  7. ^ Parthasarathy, Suhanya; Bin Azizi, Juzaili; Ramanathan, Surash; Ismail, Sabariah; Sasidharan, Sreenivasan; Said, Moh Ikram Mohd.; Mansor, Sharif Mahsufi (2009). "Evaluation of Antioxidant and Antibacterial Activities of Aqueous, Methanolic and Alkaloid Extracts from Mitragyna Speciosa (Rubiaceae Family) Leaves". Molecules. 14 (10): 3964–3974. doi:10.3390/molecules14103964. PMC 6255380. PMID 19924042.
  8. ^ Jebunnessa; Uddin, Shaikh Bokhtear; Mahabub-Uz-Zaman, Mohammed; Akter, Rasheda; Ahmed, Nazim Uddin (2009). "Antidiarrheal activity of ethanolic bark extract of Mitragyna diversifolia". Bangladesh Journal of Pharmacology. 4 (2): 144–146. doi:10.3329/bjp.v4i2.2801.
  9. ^ Ahmad, I.; Prabowo, W. C.; Arifuddin, M.; Fadraersada, J.; Indriyanti, N.; Herman, H.; Purwoko, R. Y.; Nainu, F.; Rahmadi, A.; Paramita, S.; Kuncoro, H.; Mita, N.; Narsa, A. C.; Prasetya, F.; Ibrahim, A.; Rijai, L.; Alam, G.; Mun'Im, A.; Dej-Adisai, S. (2022). "Mitragyna Species as Pharmacological Agents: From Abuse to Promising Pharmaceutical Products". Life. 12 (2): 193. Bibcode:2022Life...12..193A. doi:10.3390/life12020193. PMC 8878704. PMID 35207481.
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