In 1977, Sugandhi was elected to the Dewan Perwakilan Rakyat (DPR). She was also a member of People's Consultative Assembly. She retained her DPR membership till 1993, when Indonesian President Suharto appointed her State Minister of Women's Affairs in his Sixth Development Cabinet. For her services in this capacity, Sugandhi received the government honour Bintang Mahaputra Adipradana in 1996.
Following the May 1998 riots of Indonesia, Sugandhi was one of the prominent politicians who called for Suharto's resignation from the post of President. In 2001, she received her doctoral degree from Northern California Global University. Sugandhi was the President Commissioner of two Indonesian companies; Mitra Adiperkasa and Panen Lestari Internusa.
On 5 January 2020, Sugandhi died at the Gatot Subroto Army Hospital at age 85.
Mien was married to Indonesian general R.H. Sugandhi Kartosubroto, who was also the chairman of military welfare organisation MKGR. After his death in 1991, Sugandhi became its chairman.
- "Former women's affairs minister Mien Sugandhi dies at 85". The Jakarta Post.
- Hunter, B. (2016). The Statesman's Year-Book 1994-95. Palgrave Macmillan UK. p. 765. ISBN 978-0-230-27123-4.
- "Mien Sugandhi: Executive Profile and Biography". Bloomberg L.P. Retrieved 9 November 2017.
- Hosen, Nadirsyah (2007). Shari'a & Constitutional Reform in Indonesia. Institute of Southeast Asian Studies. p. 78. ISBN 978-981-230-402-5.
- "PMDKY Company Profile & Executives - Mitra Adiperkasa ADR". The Wall Street Journal. Retrieved 9 November 2017.
- Daves, Joseph (8 January 2015). "Golkar". The Indonesian Army. Retrieved 9 November 2017.
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