Microvascular occlusion refers to conditions that can present with retiform purpura.[1] It has been suggested that phenylephrine may be a cause.[2]
| Microvascular occlusion | |
|---|---|
| Specialty | Dermatology |
Signs and symptoms
editMicrovascular occlusions appears as bland necrosis without inflammation and retiform purpura.[3]
Causes
editMicrovascular occlusions can be caused by heparin-induced thrombocytopenia, cryoglobulinemia, angioinvasive organisms, embolization, disseminated intravascular coagulation, livedoid vasculopathy, cell occlusion syndromes, and iatrogenic causes.[3]
Outlook
editThe outcomes of microvascular occlusions are usually influenced by the degree, length, nature of the underlying cause, and prompt and effective treatment.[3]
References
edit- ^ Jean L. Bolognia; Joseph L. Jorizzo; Ronald P. Rapini (27 August 2003). Dermatology. Elsevier Health Sciences. pp. 390–. ISBN 978-0-323-02578-2. Retrieved 20 May 2011.
- ^ Kalajian, AH.; Turpen, KB.; Donovan, KO.; Malone, JC.; Callen, JP. (Oct 2007). "Phenylephrine-induced microvascular occlusion syndrome in a patient with a heterozygous factor V Leiden mutation". Arch Dermatol. 143 (10): 1314–7. doi:10.1001/archderm.143.10.1314. PMID 17938347.
- ^ a b c Dehghani, Shakiba; Abtahi-Naeini, Bahareh (2021). "COVID-19: A new cause of cutaneous microvascular occlusion syndrome". Journal of Research in Medical Sciences. 26 (1). Medknow: 119. doi:10.4103/jrms.jrms_560_21. ISSN 1735-1995. PMC 8765522.
Further reading
edit- Hosseini, Nastaran-Sadat; Babaei, Sharareh; Rahimi, Hamid; Gheissari, Alaleh; Sedaghat, Banafsheh; Pourmahdi-Boroujeni, Mahsa; Abtahi-Naeini, Bahareh (2023-08-22). "Cutaneous microvascular occlusion syndrome as the first manifestation of catastrophic lupus-associated antiphospholipid antibody syndrome: a case report". Journal of Medical Case Reports. 17 (1). doi:10.1186/s13256-023-04068-9. ISSN 1752-1947. PMC 10464427. PMID 37605287.
- Ko, Christine J.; Gehlhausen, Jeff R.; McNiff, Jennifer M. (2021). "Leukocytoclastic Vasculitis and Microvascular Occlusion". Surgical Pathology Clinics. 14 (2). Elsevier BV: 309–325. doi:10.1016/j.path.2021.01.006. ISSN 1875-9181.