Michael or Mike Abrams may refer to:
- Michael Abrams (boxer) (born 1949), English light-flyweight boxer
- Michael I. Abrams (born 1947), member of the Florida House of Representatives
- Mike Abrams (criminal) (died 1898), New York criminal and underworld figure
- Mike Abrams (psychologist) (born 1953), American psychologist
- M. H. Abrams (1912–2015), American literary critic, also known as Mike Abrams