miRTarBase [1] is a curated database of MicroRNA-Target Interactions. As a database, miRTarBase has accumulated more than fifty thousand miRNA-target interactions (MTIs), which are collected by manually surveying pertinent literature after data mining of the text systematically to filter research articles related to functional studies of miRNAs. Generally, the collected MTIs are validated experimentally by reporter assay, western blot, microarray and next-generation sequencing experiments. While containing the largest amount of validated MTIs, the miRTarBase provides the most updated collection by comparing with other similar, previously developed databases.

miRTarBase
Content
DescriptionExperimentally validated microRNA-target interactions (MTIs).
Data types
captured
miRNA-target interactions
Contact
Research centerNational Chiao Tung University
LaboratoryInstitute of Bioinformatics and Systems Biology
AuthorsSheng-Da Hsu
Primary citationHsu & al. (2011)[1]
Release date2013
Access
Websitehttp://mirtarbase.cuhk.edu.cn
Download URLhttp://mirtarbase.cuhk.edu.cn/php/download.php
Miscellaneous
Version4.5
miRTarBase improvements

See also

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References

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  1. ^ a b Hsu SD, Lin FM, Wu WY, Liang C, Huang WC, Chan WL, Tsai WT, Chen GZ, Lee CJ, Chiu CM, Chien CH, Wu MC, Huang CY, Tsou AP, Huang HD (2011). "miRTarBase: a database curates experimentally validated microRNA-target interactions". Nucleic Acids Research. 39 (Database issue): D163-9. doi:10.1093/nar/gkq1107. PMC 3013699. PMID 21071411.
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