Methyldiazinol (also known as 3,3-azo-17α-methyl-5α-dihydrotestosterone, 3-azi-17α-methyl-DHT, or 3,3-azo-17α-methyl-5α-androstan-17β-ol) is a synthetic and orally active androgen/anabolic steroid (AAS) which was never marketed.[1][2] It is a 17α-methylated derivative of dihydrotestosterone (DHT); specifically, it is the C3 azi (i.e., 3,3-azo) analogue of mestanolone (17α-methyl-DHT).[1][2] The drug has been found to possess a high ratio and dissociation of myotrophic to androgenic activity; relative to methyltestosterone, its ratio was 15 (3:0.2), among the highest observed.[1][2]

Clinical data
Other namesMethyldiazirinol; 3,3-Azo-17α-methyl-5α-dihydrotestosterone; 3,3-Azo-17α-methyl-DHT; 3,3-Azo-17α-methyl-5α-androstan-17β-ol; 3-Azi-17α-methyl-5α-androstan-17β-ol
Routes of
By mouth
Drug classAndrogen; Anabolic steroid
CAS Number
PubChem CID
Chemical and physical data
Molar mass316.489 g·mol−1
3D model (JSmol)

See alsoEdit


  1. ^ a b c Charles D. Kochakian (6 December 2012). Anabolic-Androgenic Steroids. Springer Science & Business Media. p. 385. ISBN 978-3-642-66353-6. Methyldiazinol: 3-Azi-17-methyl-5α-androstan-17β-ol: The 3-azi derivative of methandrostanolone was noted by CHURCH et al. (1965) to have a wide myotrophic:androgenic dissociation (3: 0.2) 15 relative to methyltestosterone orally, among the highest noted.
  2. ^ a b c Church, Robert F. R.; Kende, Andrew S.; Weiss, Martin J. (1965). "Diazirines. I. Some Observations on the Scope of the Ammonia-Hydroxylamine-O-sulfonic Acid Diaziridine Synthesis. The Preparation of Certain Steroid Diaziridines and Diazirines". Journal of the American Chemical Society. 87 (12): 2665–2671. doi:10.1021/ja01090a025. ISSN 0002-7863.