Methoxyqualone (2-Methoxyqualone) is a quinazolinone-class chemical compound which has been sold as a designer drug, first identified in Mongolia in 2022. It is closely related in structure to compounds such as etaqualone and nitromethaqualone which have previously been sold as designer drugs, and is presumed to have similar sedative effects.[1][2][3][4]

Methoxyqualone
Clinical data
ATC code
  • none
Identifiers
  • 3-(2-methoxyphenyl)-2-methylquinazolin-4(3H)-one
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC16H14N2O2
Molar mass266.300 g·mol−1
3D model (JSmol)
  • CC1=NC2=CC=CC=C2C(=O)N1C3=CC=CC=C3OC
  • InChI=1S/C16H14N2O2/c1-11-17-13-8-4-3-7-12(13)16(19)18(11)14-9-5-6-10-15(14)20-2/h3-10H,1-2H3
  • Key:YIEVFKLHPPPUSM-UHFFFAOYSA-N

See also edit

References edit

  1. ^ Yang H, Wang S, Qi H, Liu J, Wang Y, Gu J, et al. (July 2022). "2-Methoxyqualone, a new recreational drug, discovered from a package seized by the police: a preliminary report". Forensic Toxicology. 40 (2): 414–416. doi:10.1007/s11419-022-00626-w. PMID 36454416. S2CID 248347482.
  2. ^ Yang H, Wang Y, Liu J, Qiu S, Gu J, Bai H, et al. (January 2023). "The next addiction-causing drug class 4-quinazolinone derivatives: analyses of methaqualone analogs including recently discovered 2-methoxyqualone by different modes of mass spectrometry". Forensic Toxicology. 41 (1): 59–70. doi:10.1007/s11419-022-00631-z. PMID 36652055. S2CID 250077820.
  3. ^ Qiu S, Kang Y, Wang Y, Liu J, Yang H, Gu J, et al. (April 2023). "Quantification of a new recreational drug 2-methoxyqualone in human hair using gas chromatography-tandem mass spectrometry". Forensic Science International. 345: 111620. doi:10.1016/j.forsciint.2023.111620. PMID 36889066. S2CID 257244093.
  4. ^ Kuropka P, Zawadzki M, Szpot P (July 2023). "Emerging trends in methaqualone and analogues abuse: insights from online forums". Forensic Toxicology. 41 (2): 329–331. doi:10.1007/s11419-023-00665-x. PMID 37169943. S2CID 258638250.