Mebolazine (INN; brand names Dostalon and Roxilon; also known as dimethazine, dymethazine, di(methasterone) azine, or 2α,17α-dimethyl-5α-androstan-17β-ol-3-one azine) is a synthetic, orally active androgen/anabolic steroid (AAS) and a 17α-alkylated derivative of dihydrotestosterone (DHT) which is no longer marketed. It has a unique and unusual chemical structure, being a dimer of methasterone linked at the 3-position of the A-ring by an azine group, and reportedly acts as a prodrug of methasterone.
|Trade names||Dostalon, Roxilon|
|Other names||Dimethazine; Dymethazine; Dimethasterone azine; Di(methasterone) azine; 2α,17α-Dimethyl-5α-androstan-17β-ol-3-one azine|
|Chemical and physical data|
|Molar mass||633.018 g·mol−1|
|3D model (JSmol)|
|(what is this?)|
Since 2008, mebolazine has been used illegally as an ingredient is some dietary supplements, including vitamin B supplements, and in the United States the Food and Drug Administration has taken legal action against such manufacturers.
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- Clemens, Roger; Pressman, Peter (2015). "Nutritional and Dietary Supplements: Code or Concern". Preventive Nutrition: 47–62. doi:10.1007/978-3-319-22431-2_3. ISBN 978-3-319-22430-5.
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- See, for example: "FDA Warns Consumers About Health Risks With Healthy Life Chemistry Dietary Supplement". Food and Drug Administration.
- "Criminal Investigations (2011) Dietary Supplements Manufacturer Sentenced". Department of Justice.