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Professor Martin Edward Kreitman is an American geneticist at the University of Chicago,[5][6][7] most well known for the McDonald–Kreitman test that is used to infer the amount of adaptive evolution in population genetic studies.

Professor Martin Kreitman
Martin Edward Kreitman
Alma materHarvard University (PhD)
University of Florida
Stony Brook University (undergraduate)
Known forMcDonald–Kreitman test
AwardsMacArthur Fellows Program (1991)
Scientific career
InstitutionsUniversity of Chicago
Harvard University
Stony Brook University
University of Florida
ThesisNucleotide Sequence Variation of Alcohol dehydrogenase in Drosophila melanogaster (1983)
Doctoral advisorRichard Lewontin[1][2]
Doctoral studentsHiroshi Akashi[3]
Eli Stahl[3]
Peter Andolfatto
Casey Bergman[4]
Andrew Crawford
Bin He
Mark Allen Jensen
Fengli Liu
Susan Lott
Stephanie Rollmann



Kreitman graduated from Stony Brook University with a Bachelor of Science degree Biology in 1975, and from the University of Florida with a Master of Science degree in Zoology, in 1977. He went on to study at Harvard University, graduating with a Ph.D. in Population Genetics, specifically Nucleotide Sequence Variation of Alcohol dehydrogenase in Drosophila melanogaster[8] in 1983.[9]


The Kreitman lab does research in four main areas:[10][11][12][13]

"Functional evolution of cis-regulatory sequences (Drosophila)"[14]

"Molecular population genetics and evolution (Drosophila and Arabidopsis)"[14]

"Canalization in development and evolution (Drosophila)"[14]

"Evolutionary dynamics of disease resistance and pathogenicity (Arabidopsis)"[14]

Awards and honorsEdit

Recent PublicationsEdit


  1. ^ "On the 30th Anniversary of DNA Sequencing in Population Genetics | I wish you'd made me angry earlier". Archived from the original on 2013-08-06.
  2. ^ Keith, T. P.; Riley, M. A.; Kreitman, M.; Lewontin, R. C.; Curtis, D.; Chambers, G. (1987). "Sequence of the structural gene for xanthine dehydrogenase (rosy locus) in Drosophila melanogaster". Genetics. 116 (1): 67–73. PMC 1203122. PMID 3036646.
  3. ^ a b "Alumni | Ecology & Evolution | University of Chicago". Archived from the original on 2013-08-07.
  4. ^ Bergman, Casey M. (2001). Evolutionary analyses of transcriptional control sequences in Drosophila (PhD thesis). University of Chicago.
  5. ^
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  7. ^ Martin Kreitman's publications indexed by the Scopus bibliographic database. (subscription required)
  8. ^ Kreitman, Martin Edward (1983). Nucleotide Sequence Variation of Alcohol dehydrogenase in Drosophila melanogaster (PhD thesis). Harvard University.
  9. ^ "Archived copy". Archived from the original on 2010-06-10. Retrieved 2010-04-25.CS1 maint: Archived copy as title (link)
  10. ^ Kreitman, M. (1983). "Nucleotide polymorphism at the alcohol dehydrogenase locus of Drosophila melanogaster". Nature. 304 (5925): 412–417. doi:10.1038/304412a0. PMID 6410283.
  11. ^ McDonald, J. H.; Kreitman, Martin (1991). "Adaptive protein evolution at the Adh locus in Drosophila". Nature. 351 (6328): 652–654. doi:10.1038/351652a0. PMID 1904993.
  12. ^ Hudson, R. R.; Kreitman, M.; Aguadé, M. (1987). "A test of neutral molecular evolution based on nucleotide data". Genetics. 116 (1): 153–159. PMC 1203113. PMID 3110004.
  13. ^ Kreitman, Martin (2000). "Methods to detect selection In populations with applications to the human". Annual Review of Genomics and Human Genetics. 1: 539–559. doi:10.1146/annurev.genom.1.1.539. PMID 11701640.
  14. ^ a b c d "Faculty | Ecology & Evolution | University of Chicago". Archived from the original on 2013-08-06.
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External linksEdit