Marion Mckinley Bradford (October 28, 1946 - May 3, 2021) was an American scientist[1] who developed and patented the Bradford protein assay,[2] a method to quickly quantify the amount of protein in a sample.[3][4] His paper describing the method is among the most cited scholarly articles of all time.[5][6][7]

Marion M. Bradford
Born(1946-10-28)October 28, 1946
DiedMay 3, 2021(2021-05-03) (aged 74)
NationalityAmerican
Alma materUniversity of Georgia
Known forBradford assay
Scientific career
FieldsBiochemistry
ThesisEnzymology of penetration of the mammalian ovum (1975)
Doctoral advisorWilliam L. Williams

Biography edit

Early life and education edit

Bradford was born October 28, 1946, in Rome, Georgia, US, and received his B.A. from Shorter College there in 1967.[1] In 1971 he married Janet Holliday.[1][8] He obtained his Ph.D. in biochemistry from the University of Georgia in 1975, and his use of the Coomassie Brilliant Blue G-250 dye to detect proteins, which became known as the Bradford assay, was patented in 1976.[9]

Career edit

Bradford was employed by the University of Georgia as a research biochemist from 1977 to 1983.[1] In the latter year he joined A. E. Staley and worked in biochemical research there until his retirement.[1]

Bradford died on May 3, 2021, in Hendersonville, North Carolina.[10]

Award edit

  • 2019 - University of Georgia Distinction Award[11]

References edit

  1. ^ a b c d e American Men & Women of Science: A Biographical Directory of Today's Leaders in Physical, Biological, and Related Sciences (23 ed.). Gale Group. 2007. p. 756 (v. 1). Retrieved 12 March 2015.
  2. ^ Zagorski, Nick (February 2011). "Ruma V. Banerjee and Stephen W. Ragsdale: deciphering sulfur and carbon metabolism". ASBMB Today. Archived from the original on 2015-04-02.
  3. ^ Bradford MM (May 1976). "A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding". Anal. Biochem. 72 (1–2): 248–54. doi:10.1016/0003-2697(76)90527-3. PMID 942051. S2CID 4359292.
  4. ^ "Protein-assay reagent and method". US Patent Office. Retrieved 15 March 2010.
  5. ^ Van Noorden, Richard; Maher, Brendan; Nuzzo, Regina (29 October 2014). "The top 100 papers". Nature. 514 (7524): 550–553. Bibcode:2014Natur.514..550V. doi:10.1038/514550a. PMID 25355343.
  6. ^ Garfield, Eugene (12 February 1990). "The most cited papers of all time" (PDF). Current Comments. 13 (7): 2–14.
  7. ^ Garfield, Eugene (1998). "THE USE OF JOURNAL IMPACT FACTORS AND CITATION ANALYSIS FOR EVALUATION OF SCIENCE". The Scientist.
  8. ^ "Miss Janet Holliday weds Marion Bradford Saturday". Rome News-Tribune. June 13, 1971. p. 1-D.
  9. ^ "UGA scientist revolutionized biochemical research". Athens Banner-Herald. 27 October 2019. Retrieved 14 Apr 2020.
  10. ^ "Marion McKinley Bradford". Jackson Funeral Service.
  11. ^ Freund, Sarah (27 October 2019). "UGA researcher honored with Distinction Award". Online Athens. Athens Banner-Herald. Retrieved 13 Apr 2020.

Further reading edit