Main Avenue Historic District may refer to:
- Main Avenue Historic District (Durango, Colorado), listed on the NRHP in La Plata County, Colorado
- Main Avenue Historic District (De Pere, Wisconsin), listed on the NRHP in Brown County, Wisconsin
- North Main Avenue Historic District, Newton, North Carolina, listed on the NRHP in Catawba County, North Carolina
See also
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This disambiguation page lists articles associated with the title Main Avenue Historic District.
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