Mach 6 or variation, may refer to:
- Mach number representing 6-times the speed of sound
- Hypersonic speed of 6-times the speed of sound
- Mach 6 (album), 2003 album by MC Solaar
- Mach Six, racing car in the Speed Racer franchise
- Mach-VI, alias of the Marvel Comics character Abner Jenkins