MacIsaac is a surname. Notable people with the surname include:
- Angus MacIsaac (born 1943), English educator and businessman
- Angus MacIsaac (footballer) (1900-1944) Australian rules footballer
- Ashley MacIsaac (born 1975), Canadian fiddler
- Dave MacIsaac (born 1955), Canadian musician
- Dugald MacIsaac (1901-1961), Scottish chess player
- Kevin MacIsaac, Canadian zoologist
- Martha MacIsaac (born 1984), Canadian actress
This page lists people with the surname MacIsaac.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.