M98 or M-98 may refer to:
- M98 (New York City bus), a New York City Bus route in Manhattan
- Barrett M98, a Bolt-action sniper rifle
- Gewehr 98, a German bolt-action rifle
- Messier 98, an intermediate spiral galaxy about 60 million light-years away in the constellation Coma Berenices
- M-98 (Michigan highway), a former state highway in Michigan
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