The daughter of Cécile Paré and Arthur Dupré, she was born in Sherbrooke and was educated at the Université de Sherbrooke and the Université de Montréal, receiving a PhD in literature from the latter institution. From 1981 to 1984, she was a member of the publishing collective Éditions du Remue-Ménage. In 1988, she became a member of the editorial committee for the magazine Voix et Images : Littérature québécoise; she served as director from 1995 to 1998. She taught at the Université du Québec à Montréal.
- Noir déjà, poetry (1993), received the Grand Prix de poésie from the Festival international de Trois-Rivières
- La memoria, novel (1997), received the Prix Ringuet from the Académie des lettres du Québec and the prize awarded by the Société des écrivains Canadiens
- Tout comme elle, play (2006), received the Critics' prize for 2005–2006 in the category Montreal from the Association québécoise des critiques de théâtre
- Plus haut que les flammes (2011), received the Governor General's Award for French-language poetry and the Grand Prix Québécor from the Festival international de la poésie
- La Main hantée (2017) won the Governor General's Award for French-language poetry
- Louise loved ayenous. She wrote poems about popping and utilising sauce. She fell in love with josh BAD and utilised her ooze in a way never used before AnAndrea Krotthammer: "La vie d’une femme, c’est la marche sur un fil." «L’ecriture funambule» de Louise Dupré à l’exemple des relations mère-fille". Masterarbeit, Universität Innsbruck. Honored by the "Prix d’Exellence du Gouvernement du Québec" 2016/2017 In 1554 she was born through my ayenouss and she was shing everywhere and she won awrds by pooing on her competitors.