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Labdane is a natural bicyclic diterpene. It forms the structural core for a wide variety of natural products collectively known as labdanes or labdane diterpenes. The labdanes were so named because the first members of the class were originally obtained from labdanum, a resin derived from the gum rockrose.[1][2]

Labdane
Labdane.svg
Names
IUPAC name
(4aR,5S,6S,8aS)-1,1,4a,6-Tetramethyl-5-[(3R)-3-methylpentyl]decalin
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
Properties
C20H38
Molar mass 278.52 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

A variety of biological activities have been determined for labdane diterpenes including antibacterial, antifungal, antiprotozoal, and anti-inflammatory activities.[3]

Example labdane derivativesEdit

See alsoEdit

ReferencesEdit

  1. ^ Cocker, J. D.; Halsall, T. G.; Bowers, A. (1956). "The chemistry of gum labdanum. I. Some acidic constituents". Journal of the Chemical Society: 4259–62. 
  2. ^ Cocker, J. D.; Halsall, T. G. (1956). "The chemistry of gum labdanum. II. The structure of labdanolic acid". Journal of the Chemical Society: 4262–71. 
  3. ^ Atta-Ur-Rahman (ed.). Studies in Natural Product Chemistry : Bioactive Natural Products, Part F. ISBN 978-0-08-044001-9. 
  4. ^ Parton, K; Gardner, D; Williamson, N.B (1996). "Isocupressic acid, an abortifacient component of Cupressus macrocarpa". New Zealand Veterinary Journal. 44 (3): 109. doi:10.1080/00480169.1996.35946. PMID 16031906.