Ladinin 1

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Ladinin-1 is a protein that in humans is encoded by the LAD1 gene.[5][6][7]

LAD1
Identifiers
AliasesLAD1, LadA, ladinin 1
External IDsOMIM: 602314; MGI: 109343; HomoloGene: 4059; GeneCards: LAD1; OMA:LAD1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005558

NM_133664

RefSeq (protein)

NP_005549

NP_598425

Location (UCSC)Chr 1: 201.38 – 201.4 MbChr 1: 135.75 – 135.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene may be an anchoring filament that is a component of basement membranes. It may contribute to the stability of the association of the epithelial layers with the underlying mesenchyme.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000159166Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041782Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Marinkovich MP, Taylor TB, Keene DR, Burgeson RE, Zone JJ (Jun 1996). "LAD-1, the linear IgA bullous dermatosis autoantigen, is a novel 120-kDa anchoring filament protein synthesized by epidermal cells". J Invest Dermatol. 106 (4): 734–8. doi:10.1111/1523-1747.ep12345782. PMID 8618013.
  6. ^ Motoki K, Megahed M, LaForgia S, Uitto J (Apr 1997). "Cloning and chromosomal mapping of mouse ladinin, a novel basement membrane zone component". Genomics. 39 (3): 323–30. doi:10.1006/geno.1996.4507. PMID 9119369.
  7. ^ a b "Entrez Gene: LAD1 ladinin 1".

Further reading

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