|Date of birth||19 April 1962|
|Place of birth||Athens, Greece|
|* Senior club appearances and goals counted for the domestic league only|
Born in Athens, Antoniou started his career at Panathinaikos FC during the late 1970s. He was recognized for his offensive talent as well. While playing for Panathinaikos he won four Championships (1984, 1986, 1990, and 1991) and three Cups (1984, 1986, and 1989). In 1988, he agreed to join Olympiacos for the sum of 24 million drachma. He accepted, but the Panathinaikos president launched legal action and won an appeal for Antoniou to return. Antoniou stated in an interview: "I'm not going to return to Panathinaikos -not even dead". Antoniou then spent six months in the stands before he was able to play again. In the winter of 1994 he moved to Athinaikos, where he ended his playing career.
In May 2008, Antoniou returned to his favorite club, this time as a Director of Football. In June 2010, after the resignation of Panathinaikos' President Nicolas Pateras, Antoniou also resigned.