John Synadenos (Greek: Ἰωάννης Συναδηνός) can refer to:
- John Synadenos (megas stratopedarches) (fl. 1277–1310/28), Byzantine nobleman and general
- John Synadenos (megas konostaulos) (fl. 1320s), son of the above, Byzantine nobleman and general
This disambiguation page lists articles about people with the same name.
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