Jeffries House may refer to:
- Jeffries House (North Little Rock, Arkansas), listed on the National Register of Historic Places in Pulaski County, Arkansas
- Capt. Harold B. Jeffries House, Zephyrhills, Florida, listed on the National Register of Historic Places
- Augustine Hansell House, also known as Jeffries House, a historic house in Thomasville, Georgia
This disambiguation page lists articles associated with the title Jeffries House.
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