I-53 or Japanese submarine I-53 may refer to more than one submarine:
- Japanese submarine I-53 (1925), an Imperial Japanese Navy Type KD3 submarine launched in 1925 and decommissioned in 1945, renumbered I-153 in 1942
- Japanese submarine I-53 (1942), an Imperial Japanese Navy Type C submarine launched in 1942 and decommissioned in 1945
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.