Isaac Ledyard (November 5, 1755 or 1754 – August 28, 1803) was a physician and politician from New York.

Life

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He was born in Groton, Connecticut, the son of Youngs Ledyard (1731–1762) and Mary (Avery) Ledyard (1730–1787).

He was Health Officer for the Port of New York. Ledyard was a presidential elector in 1800, voting for Thomas Jefferson and Aaron Burr.

The town of Ledyard, Connecticut is named for his family.