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Ilo Browne Wallace (March 10, 1888 – February 22, 1981) was the wife of Henry A. Wallace, the 33rd U.S Vice President and later Secretary of Commerce. She was the Second Lady of the United States from 1941 until 1945. She was the sponsor of the battleship USS Iowa.

Ilo Wallace
Mrs. Henry Wallace.jpg
Second Lady of the United States
In role
January 20, 1941 – January 20, 1945
Vice PresidentHenry A. Wallace
Preceded byMariette Garner
Succeeded byBess Truman
Personal details
Ilo Browne

(1888-03-10)March 10, 1888
Indianola, Iowa, U.S.
DiedFebruary 22, 1981(1981-02-22) (aged 92)
South Salem, New York, U.S.
Political partyDemocratic
Henry A. Wallace
(m. 1914; died 1965)
  • Henry Browne
  • Robert
  • Jean
EducationMonmouth College

Born in Indianola, Iowa, she was the daughter of James Lytle Browne and his wife, the former Harriet Lindsay.

She attended Monmouth College with the class of 1911.

She married Henry Agard Wallace in Des Moines, Iowa, on May 20, 1914. They had three children: Henry Browne Wallace (1915–2005), Robert Browne Wallace (1918–2002), and Jean Browne Wallace (1920–2011). Her husband later became the editor-in-chief of Wallace's Farmer, an influential Midwestern farming magazine that had been founded by his father, Henry Cantwell Wallace, a future U.S. Secretary of Agriculture.

A small inheritance she received from her parents enabled the Wallaces and their business partners to establish, in 1926, the Hi-Bred Corn Company, which developed and distributed hybrid maize and eventually transformed agriculture. The company is now known as Pioneer Hi-Bred International, the world's second largest seed company.

On February 22, 1981, she died at the Wallace estate, Farvue Farm, in South Salem, New York.